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nDash Writer Profile for Tatjana Bosnjak

Headline

PhD Research Fellow - Department of Pharmaceutical Biosciences, UiO

About Me

I'm a 26 years old researcher working in the field of Pharmaceutical Biosciences. I've entered this exciting area when I was 15.

When I'm not trying to fight diseases, I'm enjoying fitness, nature, meditation, healthy foods and piano.

Industries I Write About

Science & Medicine

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Health & Wellness

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Business

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My Writing Samples

Pipetting technique: Tips to improve precision and data integrity

Scientific technique improvement tips.

https://blog.quartzy.com/2017/05/11/pipetting-technique-tips-precision-data-integrity

Electrophoresis for Western blotting: Application and tips

Scientific technique improvement tips.

https://blog.quartzy.com/2017/05/15/electrophoresis-western-blot

Western blotting: Tips to optimize a deceptively complex process

Scientific technique improvement tips.

https://blog.quartzy.com/2017/05/22/western-blotting-tips-optimize-process

Automated cell counting: Tips and techniques for optimal results

Scientific technique improvement tips.

https://blog.quartzy.com/2017/05/31/automated-cell-counting-tips-techniques

Experience

Board Member

Company: SiN - stipendiat organisasjonene i Norge

I worked there from 5/2017 until now

PhD Research Fellow

Assistant professor at the Department of Pharmacology PhD Research Fellow at the Department of Pharmaceutical Biosciences - Research Group "ProTarg" ProTarg studies proteolytic enzymes with particular focus on cysteine ​​proteases (legumain, cathepsins) and the roles of these enzymes in normal physiology and in disease. We studie enzymes that cleave proteins. Such degradation is irreversible and these enzymes are therefore potential targets for drugs. Hence the name: "PROteases as pharmacological TARGets"! When these enzymes cleave other proteins (substrates) several things can happen. The cleavage of the protein may cause activation, mediators can be released or the protein can be degraded to peptides and amino acids. These are always irreversible reactions: cells must synthesize new proteins to replace those which have been cleaved. It has been shown that proteolytic enzymes are involved in inflammatory reactions and diseases like cancer and atherosclerosis. Thus, the inhibition of these enzymes with drugs is considered to be an interesting strategy in treatment. Proteolytic enzymes are responsible for controlled cell death. To let cells die in a controlled manner is very important and if these mechanisms fail unrestricted growth can result and lead to cancer. Also, cells can die when they should continue to live. If this happens in the brain it may result in neurodegenerative diseases like Parkinson’s disease and Alzheimer’s disease. If we can understand the roles that proteases play in these diseases we hope to be able to establish a more rational treatment with drugs. We study the interaction between and the effects of drugs on cysteine ​​proteases and their endogenous inhibitors (cystatin) in cancer and atherosclerosis. The general goal of my doctoral project is tu elucidate cellular and molecular mechanisms of proteases in bone remodeling under physiological and pathological conditions of bone loss and utilizing them as pharmacological targets.

Company: Universitetet i Oslo (UiO)

I worked there from 9/2016 until now

Board Member

Company: UiODoc

I worked there from 5/2017 until now

Scientific writer

Freelance writing.

Company: Quartzy

I worked there from 4/2017 until 5/2017

Languages I Write In

Content I Write